IBM using DNA methods to keep pace with Moore’s Law

17 Aug 2009

Scientists at IBM have scored a major breakthrough in semiconductor manufacturing – using the way life’s basic architecture DNA constructs itself – to pack more power and speed into tiny computer chips.

The DNA scaffolding method also makes these next generation semiconductors more energy efficient and less expensive to manufacture.

IBM Researchers and collaborator Paul W.K. Rothmund, of the California Institute of Technology, have made an advancement in combining lithographic patterning with self assembly – a method to arrange DNA origami structures on surfaces compatible with today’s semiconductor manufacturing equipment.

Today, the semiconductor industry is faced with the challenges of developing lithographic technology for feature sizes smaller than 22 nanometers (nm) and exploring new classes of transistors that employ carbon nanotubes or silicon nanowires.

IBM’s approach of using DNA molecules as scaffolding – where millions of carbon nanotubes could be deposited and self-assembled into precise patterns by sticking to the DNA molecules – may provide a way to reach sub-22 nm lithography.

The positioned DNA nanostructures can serve as scaffolds, or miniature circuit boards, for the precise assembly of components – such as carbon nanotubes, nanowires and nanoparticles – at dimensions significantly smaller than possible with conventional semiconductor fabrication techniques.

“The cost involved in shrinking features to improve performance is a limiting factor in keeping pace with Moore’s Law and a concern across the semiconductor industry,” said Spike Narayan, manager, Science & Technology, IBM Research – Almaden.

“The combination of this directed self-assembly with today’s fabrication technology eventually could lead to substantial savings in the most expensive and challenging part of the chip-making process,” Naravan added.

The techniques for preparing DNA origami, developed at Caltech, cause single DNA molecules to self assemble in solution via a reaction between a long single strand of viral DNA and a mixture of different short synthetic oligonucleotide strands.

These short segments act as staples – effectively folding the viral DNA into the desired 2D shape through complementary base pair binding. The short staples can be modified to provide attachment sites for nanoscale components at resolutions (separation between sites) as small as 6 nanometers (nm).

In this way, DNA nanostructures such as squares, triangles and stars can be prepared with dimensions of 100 – 150 nm on an edge and a thickness of the width of the DNA double helix.

IBM uses traditional semiconductor techniques, the same used to make the chips found in today’s computers, to etch out patterns, creating the lithographic templates for this new approach. Either electron beam or optical lithography are used to create arrays of binding sites of the proper size and shape to match those of individual origami structures.

The template materials are chosen to have high selectivity so that origami binds only to the patterns of “sticky patches” and nowhere else.

By John Kennedy

John Kennedy is a journalist who served as editor of Silicon Republic for 17 years

editorial@siliconrepublic.com